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Why More Elderly People Are Needed for Clinical Trials

Recent reports have highlighted an urgent need to get more elderly people to take part in clinical trials.

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As the world’s population grows, and life expectancy also increases, the proportion of older people becomes exponentially larger.

According to The Telegraph, the number of people aged 75 and over in the UK is expected to rise to 9.9 million by the year 2039, while the number of people aged 85 and over is projected to more than double.

The worry is that if older people are not included in current and future clinical trials, for whatever reason, the true effect of the drugs or treatments being tested may not be accurate for many thousands of people in the future.

What Is the Extent of the Problem?

A recent study into breast cancer trials in America found that only 17% of those taking part were aged 65 or over, with a pitiful 15% being aged 70 or over.

In contrast, in the ‘real world’ almost a half (47%) of all deaths from breast cancer in the US happen to women aged 70 or more.

There is a real danger that testing potential treatments for cancer and other illnesses on younger women may not give the same results as on older women.

Additional Health Conditions

In addition to this fairly obvious issue, there is another factor which is adding weight to the call for more elderly patients in trials.

For various reasons, older people are far more likely to have additional pre-existing health problems, which may have an effect on the efficacy or risks of any treatments they receive.

Worldwide, common health conditions, such as obesity, diabetes, osteoporosis, dementia and hypertension (high blood pressure), are far more likely to occur in people over 65.

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Having one or more of these conditions could seriously affect a patient’s reaction to treatments or drugs. So using more elderly people – and recognising which other conditions they have – could lead to more accurate and personalised treatments and care.

Certain drugs being tested in clinical trials need to be put through thorough QT studies, such as those provided at http://www.richmondpharmacology.com/specialist-services/tqt.php, in order to determine whether they affect the heart’s rhythm.

If the drugs pass the QT studies, they can then go on to the next stage of the clinical trial process.

What different occasions can I use a marquee for?

Marquees come in a huge range of shapes and sizes, allowing them to be flexible and to have many different uses. Here are some of the best ways that a marquee can be used to suit you.

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Weddings and celebrations

Using a marquee for large celebrations has become really popular, especially when used for weddings. Lots of newlyweds have opted for a marquee, whether it’s to create extra space for their guests or simply to cut costs like this couple did. With a marquee, you have a blank canvas to work with, whilst also allowing you to take shelter from the uncertain weather.

Retail

A marquee can easily be set up, making it a perfect option for those wanting to use it for retail. You could use it as a pop up shop, on markets or at showcases, allowing the customer to feel like they are actually in a store.

Events and festivals

Not only can a marquee be put up in minutes, you can also arrange sections, making it a great choice for events which need to have different areas. You never know what the weather will be like, so a marquee will allow event attendees to use it as a well appreciated sheltered area.

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Corporate use

If you need a setup to promote your corporate business, look no further than a marquee. A temporary structure which can easily be moved or stored is the perfect option. If you’re looking for marquee hire in Kent, you can see the range available at websites such as http://www.2intents.co.uk/. If you would prefer to purchase your own marquee for corporate use, you should think about the colour and design, or even adding branding to get you noticed.

Emergencies

A marquee is the perfect solution if you need a quick and easy focal point, such as in an emergency. They make great temporary command posts, acting as a base and information point, making the area more organised and allowing others to put their focus where it’s really needed.

Whatever you need the extra space for, a marquee is a great option. They can be as big or as lightweight as you need them to be, and with a range of sizes, colours and styles, you can be sure to find something to suit.

10 more ways to add value to your home

Moving up the property ladder to your dream home means adding value to your current property to maximise the return on your investment. Here are 10 more ways to do just this.

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1. Focus on the kitchen

If you are only going to makeover one room, make it the kitchen. For most people, this is now the centrepiece of the home; however, be careful – make sure the kitchen you install is appropriate to the value of your house or you either won’t see a return or can drag the value down.

2. Spruce up the bathroom

If your ceramics are in good order, adding new taps, a power shower and a shower screen instead of a curtain can give your bathroom a quick and inexpensive makeover that adds resale value.

3. Add a shower room or en suite

If you have the space, adding a shower room or en suite will create added value. Consider moving the bathroom upstairs in a period property and adding a cloakroom.

4. Enhance your home’s character

If period features have been removed, consider adding them sympathetically. In a more modern home, try upgrading laminate floors to solid wood.

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5. Apply for planning permission

Even if you do not intend to extend, giving your buyers the option by applying for planning permission will give your property the edge.

6. Makeover the garden

Add a built-in barbecue or pizza oven, repair your fences, and tidy your borders. If you have an independent garage, consider a St Albans garage door installation from a company such as http://garagedoorsrus.co.uk/garage-door-installation-st-albans/ to add extra functionality and appeal.

7. Remodel your floor space

The desire for open-plan living shows no signs of going away, so think about ways you can open up the space in your home. Non-load-bearing walls are relatively easy to remove to create open-plan living areas and, of course, boost resale value.

8. Upgrade services

Installing the latest technology, or simply upgrading your plumbing, is a smart way to increase your property’s saleability.

9. Fix superficial flaws

Fixing dripping taps, filling ceiling cracks and replacing mouldy sealant are quick fixes to improve your home.

10. Keep it in perspective

Remember that taking the price of your property over the ceiling value for your street can be counterproductive, so consider carefully where you will really add value.

Reach Out to Combat Loneliness

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Did you know that loneliness amongst the elderly has been deemed as more dangerous than obesity? Researchers have found that loneliness can be twice as unhealthy as obesity and has a devastating impact on the lives of older people. During a six year study, people aged 50 and over were almost twice as likely to die than those who were not lonely. If you have elderly relatives or neighbours then now is the time to connect and get them out and about. Read more

The benefits of heat recovery ventilation

Many property owners are familiar with the benefits of investing in effective insulation, double glazing and extractor fans, including improved heat retention and a reduction in condensation and damp problems.

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An additional improvement that can be made is the installation of heat recovery ventilators. These systems recover the waste heat energy in the stale, exhaust air from a space and use it to warm the fresh, inlet air.

Modern building regulations require homes to be air tight, preventing draughts and heat loss; as a result, the air in the home can become stale and humid, resulting in discomfort and potential health problems.

General benefits of heat recovery ventilation

The most obvious benefit of heat recovery ventilators, which are available from suppliers such as https://www.restorationuk.com/condensation-products/single-room-heat-recovery-ventilators/product/kair-heat-recovery-room-ventilator-k-hrv150, is the energy saving potential. By using waste heat to warm up incoming air, a reduced load is placed on the boiler and heating system to heat the building, thus saving cost.

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Using heat recovery will also improve the quality of the air in the building. Contaminants such as pollen and dust will be removed, and the humidity of the air will be lower. This eliminates problems with condensation and subsequent issues with mould and damp.

Business benefits

Businesses are interested in maintaining a ‘green’ profile and reducing their carbon footprint. The large boilers used to heat commercial properties can be improved by increasing efficiency through the use of flue gas economisers. These units absorb waste heat from the flue of the boiler, which can then be reused to preheat the incoming water to the boiler, thereby reducing the energy used in heating from cold.

Employees will benefit from a consistent workplace temperature and humidity, thereby improving working conditions and raising morale and work efficiency.

Industrial applications could see even greater energy savings; without heat recovery systems, a significant quantity of heat is lost.

The future

Further developments in heat recovery technology will lead to improvements in the ability to extract waste heat from other sources in and around homes and businesses and use it to reduce energy costs and carbon footprints.

Heat recovery is not right for every property; for example, older buildings often have a greater number of draughts and heat can be lost through a variety of outlets. The cost of retrofitting heat recovery systems and associated ducting can also be expensive.

Top Beach Resorts In Phuket

Phuket is home to many excellent beaches and resorts. It is therefore a daunting task for anyone to attempt to rate the resorts. Nevertheless, this article will attempt to list some of the best resorts in Phuket based on factors like; facilities, uniqueness, clarity of the sea, quality of sandy beaches, beach intimacy, accommodation, amenities, activities among many other factors. Whichever way you choose to grade beach resorts, you will definitely find some of the best Phuket resorts in our list below. Read more

10 Benefits Of Investing In A Conservatory For Your Home

Buying and selling houses is expensive. That’s why many people are choosing to ‘improve, rather than move’.

One of the best ways to improve your home is by building a new conservatory. There are many benefits to this added extension. Let’s have a look at the top ten below.

Extra Room

One of the key benefits is the extra room you’ll get by building a conservatory. Be warned though, with extra room comes great responsibility. Don’t use this room as a mere dumping ground!

Give your conservatory a clear purpose, by creating a living area, dining area, chill out space, study area or kids’ play zone. The possibilities are endless and because conservatories are flexible spaces, you can change your conservatory’s purpose with the seasons.

Cheaper than moving Home

The average cost of moving house is over £8,000. Couple that with the stress of shifting from one home to another, and you can see why building a conservatory is much more appealing.

If you’re looking to move to increase the amount of space in your home, a conservatory is a good alternative.

Increases value of your Home

Conservatories increase property prices by around seven per cent. Building a conservatory is a sensible investment that will give your home added appeal and possibly set you apart from other houses in your neighbourhood.

Make sure you choose a conservatory that is in keeping with the style of your property and isn’t overbearing in your garden.

Enables you to enjoy the Garden year-round

Gardens aren’t just to be enjoyed during the summer months, although the great British weather does put us off from spending time outside.

With a conservatory, you get to enjoy your garden every day of the year. A professionally fitted conservatory will be warm in the winter months and cooler in the summer. This will allow you to relax comfortably, whatever the temperature is outside.

Provides a Stress-free sanctuary

Dedicate your conservatory as your family’s stress-free sanctuary and give everyone some space to relax and unwind.

There’s something about listening to raindrops in a conservatory that us humans love. It’s very calming and helps us zone out. The next time there’s a heavy rain shower or thunderstorm, enjoy this experience with your family and spend some quality time together under the glass roof.

Watch the kids play

Who doesn’t want to spend more time watching their kids enjoy themselves?

With a conservatory, gone are the days of watching them out of the kitchen window whilst you wash up. You can sink into a comfy chair, with a cup of tea and your favourite book and enjoy the laughter from your children playing in the garden.

Enjoy more natural Light

There’s no doubt about it, natural light is good for us. Why read your morning paper in the dimly light living room, when you can sit in your conservatory and open the doors to the great outside instead?

Ideal for Entertaining

Make the neighbours jealous by hosting legendary dinner parties in your conservatory.

During the winter, a snug conservatory can be transformed from a summer space, into a functional dining room. In the summer months, turn your dining room into a more flexible living area. If you’re hosting a BBQ, conservatories provide welcome cover from the hot sun, or unpredicted rain showers.

Creative study space

More people than ever before are able to work from home. That means folders, paperwork and stationery creeping into your living room or bedroom. If you’re not luck enough to have a study, the conservatory is the perfect creative space for studying and working to take place.

A neat den for the kids

Keep the kids’ toys and games out of the living room by investing in a couple of toy trunks for the conservatory. The conservatory is a great place for the kids to enjoy some playtime, whilst mum and dad relax in a tidy and organised living room. Bliss.

Although the initial cost of building a conservatory might discourage you, you should consider it as a key long-term investment.

Choose the right conservatory supplier and adhere to building regulations, and you’ll be amazed at the difference a conservatory can make to your life.

Mark Caulfield is a qualified and experienced architect and the co-founder of conservatory design company Caulfield Conservatories. Mark regularly blogs on the benefits of investing in conservatories and can provide design and installation advice to those who are thinking about adding an extension to their home.

What Common Problems Can Affect Veins?

Veins may not enjoy the same attention as other parts of the body, but they play an essential role in transporting blood to the heart to be oxygenated and are as prone to problems as any other body part. As around half of the population will have a problem with leg veins in their lifetime, this is an area of health care treatment that deserves to be centre stage.

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Anyone can develop leg vein problems, although the risk for women is double that for men. Apart from thread (spider) veins caused by malfunctions in the tiny veins called capillaries, the most common leg vein conditions people look for help with are varicose veins and chronic venous insufficiency, both caused by a problem with the circulatory system.

Varicose Veins

Experts claim that nearly 90% of the population suffer from thread veins at some point in their lifetime, and around 40% will, by the age of 50, have either visible or hidden varicose veins. Caused by faulty valves in veins failing to keep blood moving through the one way system, the result is fluid pooling which in turn stretches the veins, leaving them both prominent and painful. Varicose veins are linked to genetics, pregnancy and obesity.

Chronic Venous Insufficiency [CVI]

Varicose veins occur when blood pools at a surface level, but when the poor blood drainage occurs deeper in the tissue the condition is known as chronic venous insufficiency. Usually triggered by a historical thrombosis, CVI tends to make legs swell rather than veins, and the treatment tends to be based around aids such as support hosiery.

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Treatment for Varicose Veins

Losing weight and elevating legs can help, but the most effective treatments involve medical intervention. Contemporary medicine offers innovative and less invasive options, with day surgery heat and foam techniques which are light years away from the traditional method of stripping veins.

Anyone concerned about leg veins should seek advice from a qualified doctor. Ask for personal recommendations or do some online research to find a convenient clinic which offers a range of contemporary procedures. For example, in Cheshire varicose vein treatments are available at http://www.veinsolutions.co.uk/.

Why put up with the pain and restrictions leg vein problems can bring when simple and effective solutions are close at hand, and treatment offers improvements in health, mobility and self confidence?

Grow your own

The health benefits of aloe vera have often been cited so surely it makes sense to have an aloe vera plant in your home so you can use it, should the need arise. Having an aloe vera plant can make even the most modern and high-tech of us feel like magic herbalist practitioners. Snipping off a piece of an aloe vera’s leaf and applying the clear, cool gel on burns, cuts, rashes, and sunburns offers instant relief and can speed the healing process. If you’re new to the world of having succulents in your home then here’s how to care for an aloe vera plant of your own.

There are hundreds of varieties of aloe plants, which are indigenous to Africa and a few neighboring areas. They come in many varieties that range in size from a few inches to tree heights of 30 to 40 feet. Don’t worry, you won’t need one that big. They also come in many colours and shapes, including orange-hued, purple-tinged, and with various spine patterns. Some aloe plants will also flower. Though many might think of the aloe plant as a cactus, it is actually a succulent. The most common type is the aloe barbadensis.

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Here in the colder northern hemisphere, it’s best to keep your aloe vera plant indoors. They are hardy in warmer climates but are very susceptible to frost, because they are composed of so much water. Think of the indigenous climate of the plant and you’ll understand its ideal conditions. In the case of aloe plants, they love to be in the sun and do well in dry climates. For more information on aloe vera juice health benefits, visit gofitnesslifestyle.com

Aloe vera plants are easily available anywhere you can buy plants. The soil should be well-drained and using a cactus mix works well. The pot should have enough room for the plant to grow, particularly the root ball. When re-potting, choose a container that’s wider than the previous one, but not deeper, and with extra room equivalent to 3 to 5 times the size of the current root ball.

Aloe veras are tolerant of dry conditions, but we still need to make sure we water them. In the summer months, soak them thoroughly but allow them to dry well between waterings. This means they must be dry to a depth of 1 – 2 inches. During the winter months, water less often, if you need to at all, as the plant is dormant.

Mature aloe vera plants can be used to grow more plants through offshoots which can be removed and replanted. Tap your plant out of its pot and find where the offshoots are attached. Sever them with a knife from the main plant and then let the cut dry over before planting it, which should take a couple of days. Pot them in a standard potting mix, keep them somewhere that gets the sun and wait for a week until watering as the soil needs to be kept on the dry side.

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5 more of the best web design standards in 2017

Many businesses do not think about basic web design standards, but these are very important to web designers. A great website will meet all web design standards, which means it will be user-friendly, fast, and easy to navigate.

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If you want to make sure that your website is up to scratch, here are five of the best web design standards to meet in 2017:

A clear search button

Most websites today have a search button bar at the top of the page, which makes it easy for users to search and navigate their way around the website. If your website has a lot of content, you should consider using a search button; otherwise, users will struggle to find the information they are looking for.

A clear call to action

Your website exists for a reason – perhaps you want users to sign up to your website or newsletter, or maybe you want to sell products. Either way, it is important that there is a clear call to action at the top of your home page. This makes it easy for users to understand what they are supposed to do when they visit your website.

A mobile-friendly, responsive design

According to Ofcom, the smartphone has overtaken the laptop as the most popular device for getting online; therefore, it is important to make sure that your website uses a mobile-friendly responsive web design. This means all your visitors will have a great browsing experience, rather than only the visitors who are using laptops.

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Clear social media icons

Businesses should always promote their social media channels on their website. People who visit your website are likely to be interested in your social media pages; in addition, it is free to advertise them on your own website.

If you are looking for a company that specialises in web design in Belfast, or any other location, check out agencies such as http://www.rycomarketing.co.uk/web-design.html for affordable web design offers.

A clear sign-up box

If you want people to sign up to your website, you must make sure it has a clear sign-up box. It is often best to place the sign-up box at the bottom of the screen, with the top of the screen dedicated to a search box and a clear call to action.

 

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